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Role of Rho GDP Dissociation Inhibitor α in Control of Epithelial Sodium Channel (ENaC)-mediated Sodium Reabsorption

The epithelial sodium channel (ENaC) is expressed in the aldosterone-sensitive distal nephron where it performs sodium reabsorption from the lumen. We have recently shown that ENaC activity contributes to the development of salt-induced hypertension as a result of deficiency of EGF level. Previous s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pavlov, Tengis S., Levchenko, Vladislav, Staruschenko, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192514/
https://ncbi.nlm.nih.gov/pubmed/25164814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.558262
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