Salt-deficient diet exacerbates cystogenesis in ARPKD via epithelial sodium channel (ENaC)

BACKGROUND: Autosomal Recessive Polycystic Kidney Disease (ARPKD) is marked by cyst formation in the renal tubules, primarily in the collecting duct (CD) system, ultimately leading to end-stage renal disease. Patients with PKD are generally advised to restrict their dietary sodium intake. This study...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Ilatovskaya, Daria V., Levchenko, Vladislav, Pavlov, Tengis S., Isaeva, Elena, Klemens, Christine A., Johnson, Jessica, Liu, Pengyuan, Kriegel, Alison J., Staruschenko, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413684/
https://ncbi.nlm.nih.gov/pubmed/30745171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.01.006
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