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Nedd4-2 isoforms ubiquitinate individual epithelial sodium channel subunits and reduce surface expression and function of the epithelial sodium channel
We have previously reported the existence of multiple isoforms of human Nedd4-2 (AJP Renal 2003, 285: F916). When overexpressed in M-1 collecting duct epithelia, full length Nedd4-2 (Nedd4-2), Nedd4-2 lacking the N-terminal C2 domain (Nedd4-2ΔC2) and Nedd4-2 lacking WW domains 2 and 3 (Nedd4-2ΔWW2,3...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2008
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2424110/ https://ncbi.nlm.nih.gov/pubmed/18322022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00339.2007 |
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