Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain

Peripheral neuropathic pain is a disabling condition resulting from nerve injury. It is characterized by the dysregulation of voltage-gated sodium channels (Na(v)s) expressed in dorsal root ganglion (DRG) sensory neurons. The mechanisms underlying the altered expression of Na(v)s remain unknown. Thi...

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Hauptverfasser: Laedermann, Cédric J., Cachemaille, Matthieu, Kirschmann, Guylène, Pertin, Marie, Gosselin, Romain-Daniel, Chang, Isabelle, Albesa, Maxime, Towne, Chris, Schneider, Bernard L., Kellenberger, Stephan, Abriel, Hugues, Decosterd, Isabelle
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2013
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696561/
https://ncbi.nlm.nih.gov/pubmed/23778145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68996
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