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Neuropathic Pain Phenotype Does Not Involve the NLRP3 Inflammasome and Its End Product Interleukin-1β in the Mice Spared Nerve Injury Model

The NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome is one of the main sources of interleukin-1β (IL-1β) and is involved in several inflammatory-related pathologies. To date, its relationship with pain has not been studied in depth. The aim of our study was to elucidate the role...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Curto-Reyes, Verdad, Kirschmann, Guylène, Pertin, Marie, Drexler, Stephan K., Decosterd, Isabelle, Suter, Marc R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517753/
https://ncbi.nlm.nih.gov/pubmed/26218747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133707
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