Activation of NLRP3 inflammasome in peripheral nerve contributes to paclitaxel-induced neuropathic pain

BACKGROUND: Paclitaxel is commonly used as a cancer chemotherapy drug that frequently causes peripheral neuropathic pain. Inflammasome is a multiprotein complex consisting of Nod-like receptor proteins (NLRPs), apoptosis-associated speck-like protein, and caspase-1, which functions to switch on the...

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Publicat a:Mol Pain
Autors principals: Jia, Min, Wu, Caihua, Gao, Fang, Xiang, Hongchun, Sun, Ning, Peng, Ping, Li, Jingjing, Yuan, Xiaocui, Li, Hongping, Meng, Xianfang, Tian, Bo, Shi, Jing, Li, Man
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562344/
https://ncbi.nlm.nih.gov/pubmed/28714351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806917719804
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