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The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes
The homotypic fusion and protein sorting (HOPS) complex is a multi-subunit complex conserved from yeast to mammals that regulates late endosome and lysosome fusion. However, little is known about how the HOPS complex is recruited to lysosomes in mammalian cells. Here, we report that the small GTPase...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4432227/ https://ncbi.nlm.nih.gov/pubmed/25908847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.162651 |
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