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Lysosome-mediated plasma membrane repair is dependent on the small GTPase, Arl8b, and determines cell death type in Mtb infection

Mycobacterium tuberculosis (Mtb) is an extremely successful pathogen and its success is widely attributed to its ability to manipulate the intracellular environment of macrophages. A central phenomenon of tuberculosis pathology enabling immune evasion is the capacity of virulent Mtb (H37Rv) to induc...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Michelet, Xavier, Tuli, Amit, Gan, Huixian, Geadas, Carolina, Sharma, Mahak, Remold, Heinz G., Brenner, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995332/
https://ncbi.nlm.nih.gov/pubmed/29592961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700829
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