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The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes

Endocytic, autophagic, and phagocytic vesicles move on microtubule tracks to fuse with lysosomes. Small GTPases, such as Rab7 and Arl8b, recruit their downstream effectors to mediate this transport and fusion. However, the potential cross talk between these two GTPases is unclear. Here, we show that...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Marwaha, Rituraj, Arya, Subhash B., Jagga, Divya, Kaur, Harmeet, Tuli, Amit, Sharma, Mahak
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379943/
https://ncbi.nlm.nih.gov/pubmed/28325809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201607085
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