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Implication of Candida parapsilosis FKS1 and FKS2 Mutations in Reduced Echinocandin Susceptibility

We evaluated FKS1 and FKS2 mutations in Candida parapsilosis bloodstream isolates and correlated them with the echinocandin MIC values determined by guidelines in CLSI document M27-A3 and the YeastOne panel. All mutations detected were outside hot spot (HS) regions. The F1386S mutation detected in a...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Martí-Carrizosa, M., Sánchez-Reus, F., March, F., Cantón, E., Coll, P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432215/
https://ncbi.nlm.nih.gov/pubmed/25779577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04922-14
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