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Implication of Candida parapsilosis FKS1 and FKS2 Mutations in Reduced Echinocandin Susceptibility

We evaluated FKS1 and FKS2 mutations in Candida parapsilosis bloodstream isolates and correlated them with the echinocandin MIC values determined by guidelines in CLSI document M27-A3 and the YeastOne panel. All mutations detected were outside hot spot (HS) regions. The F1386S mutation detected in a...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Martí-Carrizosa, M., Sánchez-Reus, F., March, F., Cantón, E., Coll, P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432215/
https://ncbi.nlm.nih.gov/pubmed/25779577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04922-14
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