Implication of Candida parapsilosis FKS1 and FKS2 Mutations in Reduced Echinocandin Susceptibility

We evaluated FKS1 and FKS2 mutations in Candida parapsilosis bloodstream isolates and correlated them with the echinocandin MIC values determined by guidelines in CLSI document M27-A3 and the YeastOne panel. All mutations detected were outside hot spot (HS) regions. The F1386S mutation detected in a...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Martí-Carrizosa, M., Sánchez-Reus, F., March, F., Cantón, E., Coll, P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432215/
https://ncbi.nlm.nih.gov/pubmed/25779577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04922-14
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