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A Substrate Pharmacophore for the Human Sodium Taurocholate Co-transporting Polypeptide

Human Sodium Taurocholate Co-transporting Polypeptide (NTCP) is the main bile acid uptake transporter in the liver with the capability to translocate xenobiotics. While its inhibitor requirements have been recently characterized, its substrate requirements have not. The objectives of this study were...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Pharm
Auteurs principaux: Dong, Zhongqi, Ekins, Sean, Polli, James E.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430447/
https://ncbi.nlm.nih.gov/pubmed/25448570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2014.11.022
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