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A Substrate Pharmacophore for the Human Sodium Taurocholate Co-transporting Polypeptide

Human Sodium Taurocholate Co-transporting Polypeptide (NTCP) is the main bile acid uptake transporter in the liver with the capability to translocate xenobiotics. While its inhibitor requirements have been recently characterized, its substrate requirements have not. The objectives of this study were...

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Dettagli Bibliografici
Pubblicato in:Int J Pharm
Autori principali: Dong, Zhongqi, Ekins, Sean, Polli, James E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430447/
https://ncbi.nlm.nih.gov/pubmed/25448570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2014.11.022
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