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A Substrate Pharmacophore for the Human Sodium Taurocholate Co-transporting Polypeptide

Human Sodium Taurocholate Co-transporting Polypeptide (NTCP) is the main bile acid uptake transporter in the liver with the capability to translocate xenobiotics. While its inhibitor requirements have been recently characterized, its substrate requirements have not. The objectives of this study were...

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Detalhes bibliográficos
Publicado no:Int J Pharm
Main Authors: Dong, Zhongqi, Ekins, Sean, Polli, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430447/
https://ncbi.nlm.nih.gov/pubmed/25448570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2014.11.022
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