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Structure Activity Relationship for FDA Approved Drugs as Inhibitors of the Human Sodium Taurocholate Co-transporting Polypeptide (NTCP)

The hepatic bile acid uptake transporter Sodium Taurocholate Cotransporting Polypeptide (NTCP) is less well characterized than its ileal paralog, the Apical Sodium Dependent Bile Acid Transporter (ASBT), in terms of drug inhibition requirements. The objectives of this study were a) to identify FDA a...

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書目詳細資料
Main Authors: Dong, Zhongqi, Ekins, Sean, Polli, James E.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617406/
https://ncbi.nlm.nih.gov/pubmed/23339484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300453k
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