Natural Killer Cell Sensing of Infected Cells Compensates for MyD88 Deficiency but Not IFN-I Activity in Resistance to Mouse Cytomegalovirus

In mice, plasmacytoid dendritic cells (pDC) and natural killer (NK) cells both contribute to resistance to systemic infections with herpes viruses including mouse Cytomegalovirus (MCMV). pDCs are the major source of type I IFN (IFN-I) during MCMV infection. This response requires pDC-intrinsic MyD88...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:PLoS Pathog
Autores principales: Cocita, Clément, Guiton, Rachel, Bessou, Gilles, Chasson, Lionel, Boyron, Marilyn, Crozat, Karine, Dalod, Marc
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425567/
https://ncbi.nlm.nih.gov/pubmed/25954804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004897
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares