The Wnt Signaling Antagonist Dapper1 Accelerates Dishevelled2 Degradation via Promoting Its Ubiquitination and Aggregate-induced Autophagy

Autophagy is a regulated process that sequesters and transports cytoplasmic materials such as protein aggregates via autophagosomes to lysosomes for degradation. Dapper1 (Dpr1), an interacting protein of Dishevelled (Dvl), antagonizes Wnt signaling by promoting Dishevelled degradation via lysosomes....

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Ma, Benyu, Liu, Bofeng, Cao, Weipeng, Gao, Chan, Qi, Zhen, Ning, Yuanheng, Chen, Ye-Guang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2015
Onderwerpen:
Signal Transduction
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424364/
https://ncbi.nlm.nih.gov/pubmed/25825496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.654590
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