DNA Priming for Seasonal Influenza Vaccine: A Phase 1b Double-Blind Randomized Clinical Trial

BACKGROUND: The efficacy of current influenza vaccines is limited in vulnerable populations. DNA vaccines can be produced rapidly, and may offer a potential strategy to improve vaccine immunogenicity, indicated by studies with H5 influenza DNA vaccine prime followed by inactivated vaccine boost. MET...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ledgerwood, Julie E., Bellamy, Abbie R., Belshe, Robert, Bernstein, David I., Edupuganti, Srilatha, Patel, Shital M., Renehan, Phyllis, Zajdowicz, Thad, Schwartz, Richard, Koup, Richard, Bailer, Robert T., Yamshchikov, Galina V., Enama, Mary E., Sarwar, Uzma, Larkin, Brenda, Graham, Barney S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423975/
https://ncbi.nlm.nih.gov/pubmed/25950433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125914
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