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Lipopolysaccharide induces alveolar macrophage necrosis via CD14 and the P2x7 receptor leading to Interleukin-1α release

Acute lung injury (ALI) remains a serious health issue with little improvement in our understanding of the pathophysiology and therapeutic approaches. We investigated the mechanism that lipopolysaccharide (LPS) induces early neutrophil recruitment to lungs and increases pulmonary vascular permeabili...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Immunity
Päätekijät: Dagvadorj, Jargalsaikhan, Shimada, Kenichi, Chen, Shuang, Jones, Heather D., Tumurkhuu, Gantsetseg, Zhang, Wenxuan, Wawrowsky, Kolja A., Crother, Timothy R., Arditi, Moshe
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423803/
https://ncbi.nlm.nih.gov/pubmed/25862090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.03.007
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