Lipopolysaccharide induces alveolar macrophage necrosis via CD14 and the P2x7 receptor leading to Interleukin-1α release

Acute lung injury (ALI) remains a serious health issue with little improvement in our understanding of the pathophysiology and therapeutic approaches. We investigated the mechanism that lipopolysaccharide (LPS) induces early neutrophil recruitment to lungs and increases pulmonary vascular permeabili...

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Bibliografiske detaljer
Udgivet i:Immunity
Main Authors: Dagvadorj, Jargalsaikhan, Shimada, Kenichi, Chen, Shuang, Jones, Heather D., Tumurkhuu, Gantsetseg, Zhang, Wenxuan, Wawrowsky, Kolja A., Crother, Timothy R., Arditi, Moshe
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423803/
https://ncbi.nlm.nih.gov/pubmed/25862090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.03.007
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