Autophagy Limits Inflammasome During Chlamydia pneumoniae Infection

Autophagy can either antagonize or promote intracellular bacterial growth, depending on the pathogen. Here, we investigated the role of autophagy during a pulmonary infection with the obligate intracellular pathogen, Chlamydia pneumoniae (CP). In mouse embryonic fibroblasts (MEFs) or macrophages, de...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Crother, Timothy R., Porritt, Rebecca A., Dagvadorj, Jargalsaikhan, Tumurkhuu, Gantsetseg, Slepenkin, Anatoly V., Peterson, Ellena M., Chen, Shuang, Shimada, Kenichi, Arditi, Moshe
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6473188/
https://ncbi.nlm.nih.gov/pubmed/31031755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00754
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