Integration of G Protein α (Gα) Signaling by the Regulator of G Protein Signaling 14 (RGS14)

RGS14 contains distinct binding sites for both active (GTP-bound) and inactive (GDP-bound) forms of Gα subunits. The N-terminal regulator of G protein signaling (RGS) domain binds active Gα(i/o)-GTP, whereas the C-terminal G protein regulatory (GPR) motif binds inactive Gα(i1/3)-GDP. The molecular b...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Brown, Nicole E., Goswami, Devrishi, Branch, Mary Rose, Ramineni, Suneela, Ortlund, Eric A., Griffin, Patrick R., Hepler, John R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423691/
https://ncbi.nlm.nih.gov/pubmed/25666614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.634329
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi