John Daly Lecture: Structure-guided Drug Design for Adenosine and P2Y Receptors()

We establish structure activity relationships of extracellular nucleosides and nucleotides at G protein-coupled receptors (GPCRs), e.g. adenosine receptors (ARs) and P2Y receptors (P2YRs), respectively. We synthesize selective agents for use as pharmacological probes and potential therapeutic agents...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Jacobson, Kenneth A., Gao, Zhan-Guo, Paoletta, Silvia, Kiselev, Evgeny, Chakraborty, Saibal, Jayasekara, P. Suresh, Balasubramanian, Ramachandran, Tosh, Dilip K.
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423517/
https://ncbi.nlm.nih.gov/pubmed/25973142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2014.10.004
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