Tumor clone dynamics in lethal prostate cancer

It is unclear whether a single clone metastasizes and remains dominant over the course of lethal prostate cancer. We describe the clonal architectural heterogeneity at different stages of disease progression by sequencing serial plasma and tumor samples from 16 ERG-positive patients. By characterizi...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Carreira, Suzanne, Romanel, Alessandro, Goodall, Jane, Grist, Emily, Ferraldeschi, Roberta, Miranda, Susana, Prandi, Davide, Lorente, David, Frenel, Jean-Sebastien, Pezaro, Carmel, Omlin, Aurelius, Rodrigues, Daniel Nava, Flohr, Penelope, Tunariu, Nina, de Bono, Johann S., Demichelis, Francesca, Attard, Gerhardt
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422178/
https://ncbi.nlm.nih.gov/pubmed/25232177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3009448
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