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Design, Synthesis and Inhibitory Activity of Photoswitchable RET Kinase Inhibitors

REarranged during Transfection (RET) is a transmembrane receptor tyrosine kinase required for normal development and maintenance of neurons of the central and peripheral nervous systems. Deregulation of RET and hyperactivity of the RET kinase is intimately connected to several types of human cancers...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Ferreira, Rubén, Nilsson, Jesper R., Solano, Carlos, Andréasson, Joakim, Grøtli, Morten
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421829/
https://ncbi.nlm.nih.gov/pubmed/25944708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09769
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