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Design, Synthesis and Inhibitory Activity of Photoswitchable RET Kinase Inhibitors

REarranged during Transfection (RET) is a transmembrane receptor tyrosine kinase required for normal development and maintenance of neurons of the central and peripheral nervous systems. Deregulation of RET and hyperactivity of the RET kinase is intimately connected to several types of human cancers...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Ferreira, Rubén, Nilsson, Jesper R., Solano, Carlos, Andréasson, Joakim, Grøtli, Morten
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421829/
https://ncbi.nlm.nih.gov/pubmed/25944708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09769
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