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Design, Synthesis and Inhibitory Activity of Photoswitchable RET Kinase Inhibitors

REarranged during Transfection (RET) is a transmembrane receptor tyrosine kinase required for normal development and maintenance of neurons of the central and peripheral nervous systems. Deregulation of RET and hyperactivity of the RET kinase is intimately connected to several types of human cancers...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ferreira, Rubén, Nilsson, Jesper R., Solano, Carlos, Andréasson, Joakim, Grøtli, Morten
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421829/
https://ncbi.nlm.nih.gov/pubmed/25944708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09769
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