Brivaracetam, but not ethosuximide, reverses memory impairments in an Alzheimer’s disease mouse model

INTRODUCTION: Recent studies have shown that several strains of transgenic Alzheimer’s disease (AD) mice overexpressing the amyloid precursor protein (APP) have cortical hyperexcitability, and their results have suggested that this aberrant network activity may be a mechanism by which amyloid-β (Aβ)...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Nygaard, Haakon B, Kaufman, Adam C, Sekine-Konno, Tomoko, Huh, Linda L, Going, Hilary, Feldman, Samantha J, Kostylev, Mikhail A, Strittmatter, Stephen M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419386/
https://ncbi.nlm.nih.gov/pubmed/25945128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-015-0110-9
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