Fyn Inhibition Rescues Established Memory and Synapse Loss in Alzheimer Mice

OBJECTIVE: Currently no effective disease modifying agents exist for the treatment of AD. The Fyn tyrosine kinase is implicated in Alzheimer’s disease (AD) pathology triggered by amyloid-β oligomers (Aβo) and propagated by Tau. Thus, Fyn inhibition may prevent or delay disease progression. Here, we...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Kaufman, Adam C., Salazar, Santiago V., Haas, Laura T., Yang, Jinhee, Kostylev, Mikhail A., Jeng, Amanda T., Robinson, Sophie A., Gunther, Erik C., van Dyck, Christopher H., Nygaard, Haakon B., Strittmatter, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447598/
https://ncbi.nlm.nih.gov/pubmed/25707991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24394
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados