CCL7 and IRF7 mediate hallmark inflammatory and interferon responses following rhinovirus 1B infection: CCL7 and IRF-7 in the host response to rhinovirus

Rhinovirus infections are common and have the potential to exacerbate asthma. We have determined the lung transcriptome in RV strain 1B (RV1B) infected naïve BALB/c mice (non-allergic) and identified CCL7 and IRF7 amongst the most upregulated mRNA transcripts in the lung. To investigate their roles...

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Vydáno v:J Immunol
Hlavní autoři: Girkin, Jason, Hatchwell, Luke, Foster, Paul, Johnston, Sebastian L., Bartlett, Nathan, Collison, Adam, Mattes, Joerg
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417644/
https://ncbi.nlm.nih.gov/pubmed/25847975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401362
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