Toll-like receptor 7 governs interferon and inflammatory responses to rhinovirus and is suppressed by IL-5-induced lung eosinophilia

BACKGROUND: Asthma exacerbations represent a significant disease burden and are commonly caused by rhinovirus (RV), which is sensed by Toll-like receptors (TLR) such as TLR7. Some asthmatics have impaired interferon (IFN) responses to RV, but the underlying mechanisms of this clinically relevant obs...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Thorax
Главные авторы: Hatchwell, Luke, Collison, Adam, Girkin, Jason, Parsons, Kristy, Li, Junyao, Zhang, Jie, Phipps, Simon, Knight, Darryl, Bartlett, Nathan W, Johnston, Sebastian L, Foster, Paul S, Wark, Peter A B, Mattes, Joerg
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Publishing Group 2015
Предметы:
Respiratory Infection
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552894/
https://ncbi.nlm.nih.gov/pubmed/26108570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2014-205465
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы