Reduced IRF7 response to rhinovirus unrelated with DNA methylation in peripheral mononuclear cells of adult asthmatics

BACKGROUND: Human rhinoviruses are the major cause of asthma exacerbation in both children and adults. Recently, impaired antiviral interferon (IFN) response in asthmatics has been indicated as a primary reason of the susceptibility to respiratory virus, but the mechanism of defective IFN production...

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Vydáno v:Asia Pac Allergy
Hlavní autoři: Kim, Sae-Hoon, Lim, Kyung-Hwan, Park, Han-Ki, Lee, Suh-Young, Kim, Soon-Hee, Kang, Hye-Ryun, Park, Heung-Woo, Chang, Yoon-Seok, Cho, Sang-Heon
Médium: Artigo
Jazyk:Inglês
Vydáno: Asia Pacific Association of Allergy, Asthma and Clinical Immunology 2015
Témata:
Hypothesis & Experience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415177/
https://ncbi.nlm.nih.gov/pubmed/25938076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5415/apallergy.2015.5.2.114
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