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Molecular Underpinnings of Aprataxin RNA/DNA Deadenylase Function and Dysfunction in Neurological Disease

Eukaryotic DNA ligases seal DNA breaks in the final step of DNA replication and repair transactions via a three-step reaction mechanism that can abort if DNA ligases encounter modified DNA termini, such as the products and repair intermediates of DNA oxidation, alkylation, or the aberrant incorporat...

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Publicat a:Prog Biophys Mol Biol
Autors principals: Schellenberg, Matthew J., Tumbale, Percy P., Williams, R. Scott
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417397/
https://ncbi.nlm.nih.gov/pubmed/25637650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2015.01.007
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