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Molecular Mechanism of DNA Deadenylation by the Neurological Disease Protein Aprataxin

The human neurological disease known as ataxia with oculomotor apraxia 1 is caused by mutations in the APTX gene that encodes Aprataxin (APTX) protein. APTX is a member of the histidine triad superfamily of nucleotide hydrolases and transferases but is distinct from other family members in that it a...

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Autores principales: Rass, Ulrich, Ahel, Ivan, West, Stephen C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662222/
https://ncbi.nlm.nih.gov/pubmed/18836178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807124200
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