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Multiple Mechanisms Contribute to Inhibit Transcription in Response to DNA Damage
Cellular DNA damage elicits the phosphorylation and ubiquitination of RNA polymerase II (RNAPII), leading to the global repression of transcription. In this report we show that there are at least two different pathways to transcriptional repression, depending on the type of DNA damage. After H(2)O(2...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442283/ https://ncbi.nlm.nih.gov/pubmed/18281289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707700200 |
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