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Molecular mechanisms of topoisomerase 2 DNA–protein crosslink resolution
The compaction of DNA and the continuous action of DNA transactions, including transcription and DNA replication, create complex DNA topologies that require Type IIA Topoisomerases, which resolve DNA topological strain and control genome dynamics. The human TOP2 enzymes catalyze their reactions via...
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| Udgivet i: | Cell Mol Life Sci |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer International Publishing
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6960353/ https://ncbi.nlm.nih.gov/pubmed/31728578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03367-z |
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