Exposure of Embryonic Pancreas to Metformin Enhances the Number of Pancreatic Progenitors

AIMS: Developing beta cells are vulnerable to nutrient environmental signals. Early developmental processes that alter the number of pancreatic progenitors can determine the number of beta cells present at birth. Metformin, the most widely used oral agent for diabetes, alters intracellular energy st...

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Publicat a:Diabetologia
Autors principals: Gregg, Brigid, Elghazi, Lynda, Alejandro, Emilyn U., Smith, Michelle R., Blandino-Rosano, Manuel, El-Gabri, Deena, Cras-Méneur, Corentin, Bernal-Mizrachi, Ernesto
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417192/
https://ncbi.nlm.nih.gov/pubmed/25249235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-014-3379-5
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