mTORC1 signaling and regulation of pancreatic β-cell mass

The capacity of β cells to expand in response to insulin resistance is a critical factor in the development of type 2 diabetes. Proliferation of β cells is a major component for these adaptive responses in animal models. The extracellular signals responsible for β-cell expansion include growth facto...

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Auteurs principaux: Blandino-Rosano, Manuel, Chen, Angela Y., Scheys, Joshua O., Alejandro, Emilyn U., Gould, Aaron P., Taranukha, Tatyana, Elghazi, Lynda, Cras-Méneur, Corentin, Bernal-Mizrachi, Ernesto
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359119/
https://ncbi.nlm.nih.gov/pubmed/22544327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.20036
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