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Role of nutrients and mTOR signaling in the regulation of pancreatic progenitors development

OBJECTIVE: Poor fetal nutrition increases the risk of type 2 diabetes in the offspring at least in part by reduced embryonic β-cell growth and impaired function. However, it is not entirely clear how fetal nutrients and growth factors impact β-cells during development to alter glucose homeostasis an...

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Dettagli Bibliografici
Pubblicato in:Mol Metab
Autori principali: Elghazi, Lynda, Blandino-Rosano, Manuel, Alejandro, Emilyn, Cras-Méneur, Corentin, Bernal-Mizrachi, Ernesto
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444096/
https://ncbi.nlm.nih.gov/pubmed/28580286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.03.010
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