Exposure of Embryonic Pancreas to Metformin Enhances the Number of Pancreatic Progenitors

AIMS: Developing beta cells are vulnerable to nutrient environmental signals. Early developmental processes that alter the number of pancreatic progenitors can determine the number of beta cells present at birth. Metformin, the most widely used oral agent for diabetes, alters intracellular energy st...

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發表在:Diabetologia
Main Authors: Gregg, Brigid, Elghazi, Lynda, Alejandro, Emilyn U., Smith, Michelle R., Blandino-Rosano, Manuel, El-Gabri, Deena, Cras-Méneur, Corentin, Bernal-Mizrachi, Ernesto
格式: Artigo
語言:Inglês
出版: 2014
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417192/
https://ncbi.nlm.nih.gov/pubmed/25249235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-014-3379-5
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