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Akt/PTEN: β-cell mass and pancreas plasticity
The capacity of pancreatic β-cells to adapt to insulin resistance is critical to maintain glucose homeostasis and a factor in the development of Type 2 diabetes. The insulin receptor substrate (IRS-2/phosphoinositide 3-kinase (PI3K) pathway plays a critical role in regulating β-cell mass and functio...
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| Pubblicato in: | Trends Endocrinol Metab |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456182/ https://ncbi.nlm.nih.gov/pubmed/19541499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2009.03.002 |
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