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Heterogeneous dynamics in DNA site discrimination by the structurally homologous DNA-binding domains of ETS-family transcription factors

The ETS family of transcription factors exemplifies current uncertainty in how eukaryotic genetic regulators with overlapping DNA sequence preferences achieve target site specificity. PU.1 and Ets-1 represent archetypes for studying site discrimination by ETS proteins because their DNA-binding domai...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: He, Gaofei, Tolic, Ana, Bashkin, James K., Poon, Gregory M. K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417174/
https://ncbi.nlm.nih.gov/pubmed/25824951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv267
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