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Modulating DNA by polyamides to regulate transcription factor PU.1-DNA binding interactions
Hairpin polyamides are synthetic small molecules that bind DNA minor groove sequence-selectively and, in many sequences, induce widening of the minor groove and compression of the major groove. The structural distortion of DNA caused by polyamides has enhanced our understanding of the regulation of...
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| Publicado no: | Biochimie |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6883780/ https://ncbi.nlm.nih.gov/pubmed/31445072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2019.08.009 |
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