A Motif from Lys(216) to Lys(222) in Human BUB3 Protein Is a Nuclear Localization Signal and Critical for BUB3 Function in Mitotic Checkpoint

Human BUB3 is a key mitotic checkpoint factor that recognizes centromeric components and recruits other mitotic checkpoint molecules to the unattached kinetochore. The key amino acid residues responsible for its localization are not yet defined. In this study, we identified a motif from Lys(216) to...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Zhu, Songcheng, Jing, Ruiqi, Yang, Yiwei, Huang, Yitong, Wang, Xin, Leng, Ye, Xi, Jiajie, Wang, Guiying, Jia, Wenwen, Kang, Jiuhong
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416835/
https://ncbi.nlm.nih.gov/pubmed/25814666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.598029
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