A Motif from Lys(216) to Lys(222) in Human BUB3 Protein Is a Nuclear Localization Signal and Critical for BUB3 Function in Mitotic Checkpoint

Human BUB3 is a key mitotic checkpoint factor that recognizes centromeric components and recruits other mitotic checkpoint molecules to the unattached kinetochore. The key amino acid residues responsible for its localization are not yet defined. In this study, we identified a motif from Lys(216) to...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhu, Songcheng, Jing, Ruiqi, Yang, Yiwei, Huang, Yitong, Wang, Xin, Leng, Ye, Xi, Jiajie, Wang, Guiying, Jia, Wenwen, Kang, Jiuhong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416835/
https://ncbi.nlm.nih.gov/pubmed/25814666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.598029
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