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Structural analysis of Bub3 interactions in the mitotic spindle checkpoint
The Mad3/BubR1, Mad2, Bub1, and Bub3 proteins are gatekeepers for the transition from metaphase to anaphase. Mad3 from Saccharomyces cerevisiae has homology to Bub1 but lacks a corresponding C-terminal kinase domain. Mad3 forms a stable heterodimer with Bub3. Negative-stain electron microscopy shows...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1770893/ https://ncbi.nlm.nih.gov/pubmed/17227844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610358104 |
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