Motifs in the amino-terminus of CENP-A are required for its accumulation within the nucleus and at the centromere

Centromere protein A (CENP-A) is a variant of core histone H3 that marks the centromere's location on the chromosome. The mechanisms that target the protein to the nucleus and the centromere have not been defined. In this study, we found that deletion of the first 53 but not the first 29 residu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Jing, Ruiqi, Xi, Jiajie, Leng, Ye, Chen, Wen, Wang, Guiying, Jia, Wenwen, Kang, Jiuhong, Zhu, Songcheng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522188/
https://ncbi.nlm.nih.gov/pubmed/28489565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17204
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