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The Rho GTPase Cdc42 Is Essential for the Activation and Function of Mature B Cells

The Rho GTPase Cdc42 coordinates regulation of the actin and the microtubule cytoskeleton by binding and activating the Wiskott–Aldrich syndrome protein. We sought to define the role of intrinsic expression of Cdc42 by mature B cells in their activation and function. Mice with inducible deletion of...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Gerasimcik, Natalija, Dahlberg, Carin I. M., Baptista, Marisa A. P., Massaad, Michel J., Geha, Raif S., Westerberg, Lisa S., Severinson, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416737/
https://ncbi.nlm.nih.gov/pubmed/25870239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401634
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