The Rho GTPase Cdc42 Is Essential for the Activation and Function of Mature B Cells

The Rho GTPase Cdc42 coordinates regulation of the actin and the microtubule cytoskeleton by binding and activating the Wiskott–Aldrich syndrome protein. We sought to define the role of intrinsic expression of Cdc42 by mature B cells in their activation and function. Mice with inducible deletion of...

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Bibliografske podrobnosti
izdano v:J Immunol
Main Authors: Gerasimcik, Natalija, Dahlberg, Carin I. M., Baptista, Marisa A. P., Massaad, Michel J., Geha, Raif S., Westerberg, Lisa S., Severinson, Eva
Format: Artigo
Jezik:Inglês
Izdano: AAI 2015
Teme:
Immune Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416737/
https://ncbi.nlm.nih.gov/pubmed/25870239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401634
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