The Small Rho GTPases Rac1 and Rac2 Are Important for T-Cell Independent Antigen Responses and for Suppressing Switching to IgG2b in Mice

The Rho GTPases Cdc42, Rac1, and Rac2 coordinate receptor signaling to cell adhesion, migration, and proliferation. Deletion of Rac1 and Rac2 early during B cell development leads to failure in B cell entry into the splenic white pulp. Here, we sought to understand the role of Rac1 and Rac2 in B cel...

Full description

Saved in:
Bibliographic Details
Published in:Front Immunol
Main Authors: Gerasimčik, Natalija, He, Minghui, Dahlberg, Carin I. M., Kuznetsov, Nikolai V., Severinson, Eva, Westerberg, Lisa S.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635268/
https://ncbi.nlm.nih.gov/pubmed/29056938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01264
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items