The Rho GTPase Cdc42 Is Essential for the Activation and Function of Mature B Cells

The Rho GTPase Cdc42 coordinates regulation of the actin and the microtubule cytoskeleton by binding and activating the Wiskott–Aldrich syndrome protein. We sought to define the role of intrinsic expression of Cdc42 by mature B cells in their activation and function. Mice with inducible deletion of...

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Bibliografiska uppgifter
I publikationen:J Immunol
Huvudupphovsmän: Gerasimcik, Natalija, Dahlberg, Carin I. M., Baptista, Marisa A. P., Massaad, Michel J., Geha, Raif S., Westerberg, Lisa S., Severinson, Eva
Materialtyp: Artigo
Språk:Inglês
Publicerad: AAI 2015
Ämnen:
Immune Regulation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416737/
https://ncbi.nlm.nih.gov/pubmed/25870239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401634
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