The Rho GTPase Cdc42 Is Essential for the Activation and Function of Mature B Cells

The Rho GTPase Cdc42 coordinates regulation of the actin and the microtubule cytoskeleton by binding and activating the Wiskott–Aldrich syndrome protein. We sought to define the role of intrinsic expression of Cdc42 by mature B cells in their activation and function. Mice with inducible deletion of...

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Dettagli Bibliografici
Pubblicato in:J Immunol
Autori principali: Gerasimcik, Natalija, Dahlberg, Carin I. M., Baptista, Marisa A. P., Massaad, Michel J., Geha, Raif S., Westerberg, Lisa S., Severinson, Eva
Natura: Artigo
Lingua:Inglês
Pubblicazione: AAI 2015
Soggetti:
Immune Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416737/
https://ncbi.nlm.nih.gov/pubmed/25870239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401634
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